Event Title

Determining Colorectal Carcinoma Treatment Effectiveness Using a Fractional Order Calculus (FROC) Model

Session Number

B04

Advisor(s)

Frederick Damen, University of Illinois at Chicago
Xiaohong Joe Zhou, University of Illinois at Chicago

Location

B-125 Tellabs

Start Date

28-4-2016 8:00 AM

End Date

28-4-2016 8:25 AM

Disciplines

Biomedical Engineering and Bioengineering

Abstract

Diffusion Weighted Magnetic Resonance Imaging observes the diffusion of water through tissue. Diffusion of water attenuates the signal received. The purpose of this study was to determine if the Fractional Order Calculus (FROC) model can be used to determine if the treatment of colorectal cancer patients is effective over the duration of radiation therapy. Sixty-eight patient datasets were collected and analyzed. Regions of interests (ROI) were drawn over colorectal tumors. The variables D0, beta, and mu describe properties of tumor tissue, and were used to determine if the treatment was effective over the duration of radiation therapy. A Mann-Whitney U- test was used to analyze the ROI information. The difference in the parameter values between the initial time point and each of the two following time points was not statically significant (P > 0.05). The FROC model was not able to determine if colorectal cancer treatment was effective.


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Apr 28th, 8:00 AM Apr 28th, 8:25 AM

Determining Colorectal Carcinoma Treatment Effectiveness Using a Fractional Order Calculus (FROC) Model

B-125 Tellabs

Diffusion Weighted Magnetic Resonance Imaging observes the diffusion of water through tissue. Diffusion of water attenuates the signal received. The purpose of this study was to determine if the Fractional Order Calculus (FROC) model can be used to determine if the treatment of colorectal cancer patients is effective over the duration of radiation therapy. Sixty-eight patient datasets were collected and analyzed. Regions of interests (ROI) were drawn over colorectal tumors. The variables D0, beta, and mu describe properties of tumor tissue, and were used to determine if the treatment was effective over the duration of radiation therapy. A Mann-Whitney U- test was used to analyze the ROI information. The difference in the parameter values between the initial time point and each of the two following time points was not statically significant (P > 0.05). The FROC model was not able to determine if colorectal cancer treatment was effective.