Event Title

Telomere Length Versus Cotinine, Cadmium, and Lead Exposure

Session Number

C21

Advisor(s)

Brandon Pierce, University of Chicago

Location

A-115

Start Date

28-4-2016 1:10 PM

End Date

28-4-2016 1:35 PM

Disciplines

Biology

Abstract

The purpose of this investigation was to compare leukocyte telomere length with cotinine, cadmium, and lead exposure in the US population. Telomere length has been shown to negatively correlate with biological aging and it has been shown as a marker for many age related disease. Leukocyte telomere length has been connected with many dietary conditions, including the exposure of different metals. All data was analyzed using the program R to model a linear regression. This study, using the data from the National Health and Nutrition Examination Survey from the years 2001 – 2002, found a linear fit between mean telomere length and the before mentioned metal exposure. This was adjusted for age, and sex. Telomere length was found to be negatively correlated with cotinine (p-value: 0.7795) and cadmium (pvalues: 0.586) and positively correlated with lead (p-value: 0.1103), but the results were not significant.


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Apr 28th, 1:10 PM Apr 28th, 1:35 PM

Telomere Length Versus Cotinine, Cadmium, and Lead Exposure

A-115

The purpose of this investigation was to compare leukocyte telomere length with cotinine, cadmium, and lead exposure in the US population. Telomere length has been shown to negatively correlate with biological aging and it has been shown as a marker for many age related disease. Leukocyte telomere length has been connected with many dietary conditions, including the exposure of different metals. All data was analyzed using the program R to model a linear regression. This study, using the data from the National Health and Nutrition Examination Survey from the years 2001 – 2002, found a linear fit between mean telomere length and the before mentioned metal exposure. This was adjusted for age, and sex. Telomere length was found to be negatively correlated with cotinine (p-value: 0.7795) and cadmium (pvalues: 0.586) and positively correlated with lead (p-value: 0.1103), but the results were not significant.