Document Type

Conference Paper/Presentation

Publication Date

4-2015

Advisor(s)

Todd B. Parrish, PhD; Northwestern University, Department of Radiology

Disciplines

Education

Abstract

Parkinson's disease (PD) is characterized by the degeneration of nigrostriatal dopaminergic neurons, resulting in dysfunctional cortico­-striato-­thalamic­cortical loops. Parkinson's disease patients suffer from chronic movement disabilities as well as cognitive impairments and other nonmotor symptoms, which implies a system­wide effect on overall brain function. Because the disease currently has no cure, the discovery of a biomarker for specific PD symptoms is crucial for monitoring treatment potency. This study aimed to evaluate the validity of using functional connectivity between regions of the basal ganglia as a biomarker for specific symptoms of PD.

Comments

Presented at the ASNR 53rd Annual Meeting and Symposium, April 25-30, 2015, Chicago, IL (Neal Modi, Todd Parrish, Lucy Yuan, Xue Wang, Darren Gitemlan, Tanya Simuni, Xiaowei Song); 40th Annual Chicago Region Junior Science and Humanities Symposium Finalist; Illinois Junior Academy of Science, Region V Project Exposition Finalist

ASNR_Abstract_2015(1).pdf (258 kB)
Complete Abstract with Supporting Files

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