The Antimicrobial Properties of Z. officinale mixed with Zeolite Clinoptilolite Nanoparticles
Session Number
Project ID: MEDH 12
Advisor(s)
Dr. John Thurmond; Illinois Mathematics and Science Academy
Discipline
Medical and Health Sciences
Start Date
22-4-2020 10:05 AM
End Date
22-4-2020 10:20 AM
Abstract
There is a need for new antimicrobials, as there is an increase in existing antibiotics failing due to antibiotic resistance. In this experiment, we used the Kirby-Bauer method to test the antimicrobial properties of nanoparticles, specifically zeolite clinoptilolite, mixed with gingerol extracted with common solvents. Solvents we used to extract the active compound in ginger were ethanol, methanol, and deionized water. There were two methods used to extract the active compound in ginger. Bacteria utilized were B. subtilis, E. raffinosus, A. baylyi, P. putida, P. fluorescens, and E. coli. Results demonstrate that when ginger extracted with ethanol is combined with zeolite clinoptilolite into a nanoparticle, it exhibits antimicrobial properties against Acinetobacter baylyi, a bacteria that causes various diseases from urinary tract infections to secondary meningitis.
Keywords: antimicrobial, nanoparticles, gingerol, bacteria
The Antimicrobial Properties of Z. officinale mixed with Zeolite Clinoptilolite Nanoparticles
There is a need for new antimicrobials, as there is an increase in existing antibiotics failing due to antibiotic resistance. In this experiment, we used the Kirby-Bauer method to test the antimicrobial properties of nanoparticles, specifically zeolite clinoptilolite, mixed with gingerol extracted with common solvents. Solvents we used to extract the active compound in ginger were ethanol, methanol, and deionized water. There were two methods used to extract the active compound in ginger. Bacteria utilized were B. subtilis, E. raffinosus, A. baylyi, P. putida, P. fluorescens, and E. coli. Results demonstrate that when ginger extracted with ethanol is combined with zeolite clinoptilolite into a nanoparticle, it exhibits antimicrobial properties against Acinetobacter baylyi, a bacteria that causes various diseases from urinary tract infections to secondary meningitis.
Keywords: antimicrobial, nanoparticles, gingerol, bacteria