Event Title

The Effect of Vitamin D on Glioblastoma Multiforme T98G Cells

Session Number

Project ID: BIO 10

Advisor(s)

Dr. Sowmya Anjur, Illinois Mathematics and Science Academy

Discipline

Biology

Start Date

20-4-2022 9:10 AM

End Date

20-4-2022 9:25 AM

Abstract

Vitamin D has been proven to have anti-proliferative effects on several different types of cancer, including Glioblastoma multiforme (GBM). The use of supplemental Vitamin D has demonstrated a reduced mortality rate in GBM patients, and the expression of the Vitamin D Receptor may be associated with a better prognosis for GBM patients. To further establish the tumoricidal efficacy of Vitamin D, GBM was cultured in Vitamin D solutions of varying concentrations. We anticipate proving that Vitamin D induces apoptosis of GBM T98G cells and also confirming the proper concentration(s) of Vitamin D that may be expected to inhibit GBM cell growth.

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Apr 20th, 9:10 AM Apr 20th, 9:25 AM

The Effect of Vitamin D on Glioblastoma Multiforme T98G Cells

Vitamin D has been proven to have anti-proliferative effects on several different types of cancer, including Glioblastoma multiforme (GBM). The use of supplemental Vitamin D has demonstrated a reduced mortality rate in GBM patients, and the expression of the Vitamin D Receptor may be associated with a better prognosis for GBM patients. To further establish the tumoricidal efficacy of Vitamin D, GBM was cultured in Vitamin D solutions of varying concentrations. We anticipate proving that Vitamin D induces apoptosis of GBM T98G cells and also confirming the proper concentration(s) of Vitamin D that may be expected to inhibit GBM cell growth.