Document Type

Conference Paper/Presentation

Publication Date



Todd B. Parrish, PhD; Northwestern University, Department of Radiology


Illinois Mathematics and Science Academy, IMSA, STEM, residential high school, gifted, student inquiry, student research, Parkinson's Disease, functional connectivity




Parkinson's disease (PD) is characterized by the degeneration of nigrostriatal dopaminergic neurons, resulting in dysfunctional cortico­-striato-­thalamic­cortical loops. Parkinson's disease patients suffer from chronic movement disabilities as well as cognitive impairments and other nonmotor symptoms, which implies a system­wide effect on overall brain function. Because the disease currently has no cure, the discovery of a biomarker for specific PD symptoms is crucial for monitoring treatment potency. This study aimed to evaluate the validity of using functional connectivity between regions of the basal ganglia as a biomarker for specific symptoms of PD.


Presented at the ASNR 53rd Annual Meeting and Symposium, April 25-30, 2015, Chicago, IL (Neal Modi, Todd Parrish, Lucy Yuan, Xue Wang, Darren Gitemlan, Tanya Simuni, Xiaowei Song); 40th Annual Chicago Region Junior Science and Humanities Symposium Finalist; Illinois Junior Academy of Science, Region V Project Exposition Finalist

ASNR_Abstract_2015(1).pdf (258 kB)
Complete Abstract with Supporting Files

Included in

Education Commons



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.