Document Type

Conference Paper/Presentation


2019 Korea Science Academy Science Fair (KSASF)

Publication Date



Kirsten Viola, Northwestern University

William Klein, Ph.D., Northwestern University


Aβ Oligomers (called AβOs) are small peptides that show early build-up in immunohistochemistry and immunochemistry studies, and appear before plaques in Alzheimer’s development. High levels of AβOs cause loss of memory performance and other pathological changes.Early presentation of AβOs makes them ideal for diagnostic targeting with AβO-specific antibodies Bound to magnetic nanostructures (MNSs) for MRI visibility. Further testing can determine effectiveness of future pharmaceuticals for AD therapy.



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