Title

The Expression of ERE and NFkB & The Characterization of Stem Cell Properties in ER+ Breast Cancer Cell Lines

Authors

Utsa Bhattacharyya '21, Illinois Mathematics and Science AcademyFollow

Streaming Media

Document Type

Conference Paper/Presentation

Conference

Presented at Japan Super Science Fair (JSSF) 2020

Publication Date

10-2020

Advisor(s)

Jonna Frasor, PhD; University of Illinois, Chicago

Abstract

There is a correlation between NFkB, a transcription factor pathway, and estrogen receptor (ER) in ER+ breast cancer. We examined levels of expression with ER element (ERE) and NFkB, attempting to find a clone cell line representing the bulk population. Colonies were grown with transfected plasmids which showed NFkB/ER activity with GFP and mCherry respectively. After a week, the resulting Celigo scans were graphed. Clones 30 and 31 are the best representatives and can be used in future studies.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.

Recommended Citation

Bhattacharyya, U. (2020). The Expression of ERE and NFkB & The Characterization of Stem Cell Properties in ER+ Breast Cancer Cell Lines.
Retrieved from: https://digitalcommons.imsa.edu/student_pr/73