Event Title

Synthesis of Treatments for Mycetoma Disease

Session Number

Project ID: CHEM 10

Advisor(s)

Dr. John Thurmond; Illinois Mathematics and Science Academy

Discipline

Chemistry

Start Date

20-4-2022 8:50 AM

End Date

20-4-2022 9:05 AM

Abstract

Mycetoma is a commonly neglected tropical disease that leads to the development of tumors that may affect underlying bone (CDC, 2020). By carrying on from graduated students’ research from the previous year, we have analyzed a compound, Methyl Ether 6, that they have deemed as potentially fit for the treatment of the disease. Enforcing Lipinski’s rule of 5 in combination with thin-layer chromatography allowed us to establish groups of compound mixtures that could potentially be combined to treat Mycetoma. Running NMR tests on the subsequent groups revealed that there was indeed a group of compound mixtures that may be potentially effective in treating the disease.

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Apr 20th, 8:50 AM Apr 20th, 9:05 AM

Synthesis of Treatments for Mycetoma Disease

Mycetoma is a commonly neglected tropical disease that leads to the development of tumors that may affect underlying bone (CDC, 2020). By carrying on from graduated students’ research from the previous year, we have analyzed a compound, Methyl Ether 6, that they have deemed as potentially fit for the treatment of the disease. Enforcing Lipinski’s rule of 5 in combination with thin-layer chromatography allowed us to establish groups of compound mixtures that could potentially be combined to treat Mycetoma. Running NMR tests on the subsequent groups revealed that there was indeed a group of compound mixtures that may be potentially effective in treating the disease.