Leishmaniasis: hit to lead synthesis of treatment
Session Number
Project ID: CHEM 18
Advisor(s)
Dr. John Thurmond, Illinois Mathematics and Science Academy
Discipline
Chemistry
Start Date
20-4-2022 9:10 AM
End Date
20-4-2022 9:25 AM
Abstract
Leishmaniasis is a parasitic disease that is characterized by fevers, enlarged spleens, weight loss, and swollen glands. It primarily affects the tropical and subtropical regions of Earth, and is also classified as a neglected tropical disease. This study was done in collaboration with the Drugs for Neglected Diseases Initiative (DNDi) and the University of Otago. The goal of this project is to synthesize potential treatments for Leishmaniasis. One compound was synthesized and the structure was confirmed by nuclear magnetic resonance (NMR). This compound, and any others that are synthesized, will be sent to the University of Otago for biological testing and the results will be used to design more potent compounds.
Leishmaniasis: hit to lead synthesis of treatment
Leishmaniasis is a parasitic disease that is characterized by fevers, enlarged spleens, weight loss, and swollen glands. It primarily affects the tropical and subtropical regions of Earth, and is also classified as a neglected tropical disease. This study was done in collaboration with the Drugs for Neglected Diseases Initiative (DNDi) and the University of Otago. The goal of this project is to synthesize potential treatments for Leishmaniasis. One compound was synthesized and the structure was confirmed by nuclear magnetic resonance (NMR). This compound, and any others that are synthesized, will be sent to the University of Otago for biological testing and the results will be used to design more potent compounds.