Document Type
Article
Publication Date
1992
Description
Human chromosome 16 is the main focus of the mapping efforts at Los Alamos. The large photomicrograph on these opening pages illustrates the starting point for those mapping efforts, the evaluation of our chromosome-16-specific library of cloned fragments. Among the 23 pairs of human chromosomes, one pair, chromosome 16, is identified by fluorescence in-situ hybridization. Thousands of yellow fluorescent probes derived from the clone library have hybridized to both copies of chromosome 16. The high density and uniform coverage of the fluorescent signals were a strong indication that we could use the library to construct a map of overlapping cloned fragments spanning the entire length of the chromosome.
Recommended Citation
Courtesy of Los Alamos National Laboratory, February 2016
Included in
Bioinformatics Commons, Curriculum and Instruction Commons, Genomics Commons, Science and Mathematics Education Commons
Comments
Courtesy of Oak Ridge National Laboratory, U.S. Dept. of Energy.