Telomere Length Versus Cotinine, Cadmium, and Lead Exposure
Session Number
C21
Advisor(s)
Brandon Pierce, University of Chicago
Location
A-115
Start Date
28-4-2016 1:10 PM
End Date
28-4-2016 1:35 PM
Abstract
The purpose of this investigation was to compare leukocyte telomere length with cotinine, cadmium, and lead exposure in the US population. Telomere length has been shown to negatively correlate with biological aging and it has been shown as a marker for many age related disease. Leukocyte telomere length has been connected with many dietary conditions, including the exposure of different metals. All data was analyzed using the program R to model a linear regression. This study, using the data from the National Health and Nutrition Examination Survey from the years 2001 – 2002, found a linear fit between mean telomere length and the before mentioned metal exposure. This was adjusted for age, and sex. Telomere length was found to be negatively correlated with cotinine (p-value: 0.7795) and cadmium (pvalues: 0.586) and positively correlated with lead (p-value: 0.1103), but the results were not significant.
Telomere Length Versus Cotinine, Cadmium, and Lead Exposure
A-115
The purpose of this investigation was to compare leukocyte telomere length with cotinine, cadmium, and lead exposure in the US population. Telomere length has been shown to negatively correlate with biological aging and it has been shown as a marker for many age related disease. Leukocyte telomere length has been connected with many dietary conditions, including the exposure of different metals. All data was analyzed using the program R to model a linear regression. This study, using the data from the National Health and Nutrition Examination Survey from the years 2001 – 2002, found a linear fit between mean telomere length and the before mentioned metal exposure. This was adjusted for age, and sex. Telomere length was found to be negatively correlated with cotinine (p-value: 0.7795) and cadmium (pvalues: 0.586) and positively correlated with lead (p-value: 0.1103), but the results were not significant.