Session 2F: Exploring the Role of High Mobility Group Box 1 (HMGB1) Protein in Inflammatory Bowel Disease

Session Number

Session 2F: 1st Presentation

Advisor(s)

Eugene Chang, University of Chicago

Location

Room A115

Start Date

28-4-2017 10:00 AM

End Date

28-4-2017 11:15 AM

Abstract

Inflammatory bowel disease (IBD) is a group of diseases which affect the digestive tract. Over three million people from the United States and Europe are afflicted with an IBD (Raffals, 2016). Ulcerative colitis (UC) and Crohn’s disease (CD) are two such diseases that fall within the category of IBDs. While the exact cause of these IBDs is unknown, scientists have pointed to genetics and the environment for the onset of these illnesses. This review will explore the link between the gene High Mobility Group Box Protein 1 (HMGB1) and IBDs. A theoretical experiment that could be utilized to discover if oxidative stress is present within an organism and the implications it has in relation to IBDs is discussed.

Comments

Additional team members: Dr. Murat Eren

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Apr 28th, 10:00 AM Apr 28th, 11:15 AM

Session 2F: Exploring the Role of High Mobility Group Box 1 (HMGB1) Protein in Inflammatory Bowel Disease

Room A115

Inflammatory bowel disease (IBD) is a group of diseases which affect the digestive tract. Over three million people from the United States and Europe are afflicted with an IBD (Raffals, 2016). Ulcerative colitis (UC) and Crohn’s disease (CD) are two such diseases that fall within the category of IBDs. While the exact cause of these IBDs is unknown, scientists have pointed to genetics and the environment for the onset of these illnesses. This review will explore the link between the gene High Mobility Group Box Protein 1 (HMGB1) and IBDs. A theoretical experiment that could be utilized to discover if oxidative stress is present within an organism and the implications it has in relation to IBDs is discussed.