Session 1H: Creating a Bio-compatible Device for Intravital Culture of Skin Stem Cells and Tissue Regeneration
Session Number
Session 1H: 1st Presentation
Advisor(s)
Dr. Xiaoyang Wu, University of Chicago
Location
Room A117
Start Date
26-4-2018 9:40 AM
End Date
26-4-2018 10:25 AM
Abstract
We combined polymer synthesis and drug capsule release to create a capsule that will effectively release a drug, allowing for the direct administration and expansion of skin somatic stem cells. The support of these cells on a skin wound effectively accelerates wound healing. The researchers used biocompatible and biodegradable materials to create a hydrogel that will contain a capsule created from a reverse emulsion process. The focus was to develop a timed delayed drug release system that will result in improved drug effectiveness in vivo, reduced side effects, and a tailored dose delivery. The capsule was created with materials that allowed it to slowly degrade. Initially, the capsule release was tested in vitro and after being successfully delayed, the capsule is currently being tested in vivo using mice. This product may serve as a prototype for future treatment of massive skin wounds, preventing the infection, dehydration, and other complications that may occur due to unhealed skin wounds
Session 1H: Creating a Bio-compatible Device for Intravital Culture of Skin Stem Cells and Tissue Regeneration
Room A117
We combined polymer synthesis and drug capsule release to create a capsule that will effectively release a drug, allowing for the direct administration and expansion of skin somatic stem cells. The support of these cells on a skin wound effectively accelerates wound healing. The researchers used biocompatible and biodegradable materials to create a hydrogel that will contain a capsule created from a reverse emulsion process. The focus was to develop a timed delayed drug release system that will result in improved drug effectiveness in vivo, reduced side effects, and a tailored dose delivery. The capsule was created with materials that allowed it to slowly degrade. Initially, the capsule release was tested in vitro and after being successfully delayed, the capsule is currently being tested in vivo using mice. This product may serve as a prototype for future treatment of massive skin wounds, preventing the infection, dehydration, and other complications that may occur due to unhealed skin wounds