Event Title

Session 1H: Creating a Bio-compatible Device for Intravital Culture of Skin Stem Cells and Tissue Regeneration

Session Number

Session 1H: 1st Presentation

Advisor(s)

Dr. Xiaoyang Wu, University of Chicago

Location

Room A117

Start Date

26-4-2018 9:40 AM

End Date

26-4-2018 10:25 AM

Abstract

We combined polymer synthesis and drug capsule release to create a capsule that will effectively release a drug, allowing for the direct administration and expansion of skin somatic stem cells. The support of these cells on a skin wound effectively accelerates wound healing. The researchers used biocompatible and biodegradable materials to create a hydrogel that will contain a capsule created from a reverse emulsion process. The focus was to develop a timed delayed drug release system that will result in improved drug effectiveness in vivo, reduced side effects, and a tailored dose delivery. The capsule was created with materials that allowed it to slowly degrade. Initially, the capsule release was tested in vitro and after being successfully delayed, the capsule is currently being tested in vivo using mice. This product may serve as a prototype for future treatment of massive skin wounds, preventing the infection, dehydration, and other complications that may occur due to unhealed skin wounds

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Apr 26th, 9:40 AM Apr 26th, 10:25 AM

Session 1H: Creating a Bio-compatible Device for Intravital Culture of Skin Stem Cells and Tissue Regeneration

Room A117

We combined polymer synthesis and drug capsule release to create a capsule that will effectively release a drug, allowing for the direct administration and expansion of skin somatic stem cells. The support of these cells on a skin wound effectively accelerates wound healing. The researchers used biocompatible and biodegradable materials to create a hydrogel that will contain a capsule created from a reverse emulsion process. The focus was to develop a timed delayed drug release system that will result in improved drug effectiveness in vivo, reduced side effects, and a tailored dose delivery. The capsule was created with materials that allowed it to slowly degrade. Initially, the capsule release was tested in vitro and after being successfully delayed, the capsule is currently being tested in vivo using mice. This product may serve as a prototype for future treatment of massive skin wounds, preventing the infection, dehydration, and other complications that may occur due to unhealed skin wounds