Assessing the Impact of Glasgow Coma Scale (GCS) Score Transitions in the First 24 Hours on Clinical Outcomes in Patients with Traumatic Brain Injury (TBI)
Session Number
Project ID: MEDH 31
Advisor(s)
Ali Mansour, University of Chicago
Discipline
Medical and Health Sciences
Start Date
17-4-2024 9:20 AM
End Date
17-4-2024 9:35 AM
Abstract
Traumatic Brain Injuries (TBI) pose a substantial global health threat, representing a significant contributor to mortality rates worldwide. TBI is brain damage caused by external force, with varying severity from mild to severe, which can be classified using the Glasgow Coma Scale (GCS). This study aims to investigate the impact of GCS score transitions of penetrating and severe TBI patients from time of admittance to after 24 hours. Data from the Medical Information Mart in Intensive Care (MIMIC)-IV V2.2, at Beth Israel Deaconess Medical Center, was used to run analysis on admission characteristics of TBI patients. Two separate logistic regression models were fitted: one for mortality and one for dispositional outcome. Each model compared data of various patient variables such as Glasgow Coma Scale (GCS), ICU length of stay (LOS), age, gender, and race on the mortality and dispositional outcome of traumatic brain injury (TBI) patients. The data analysis supported that the odds of unfavorable conditions of dispositional outcome and mortality decreased by a factor of 0.136866 and 0.397105 respectively for every one unit increase of GCS. These findings provide crucial insights for enhancing clinical strategies and optimizing care for TBI patients within hospital settings.
Assessing the Impact of Glasgow Coma Scale (GCS) Score Transitions in the First 24 Hours on Clinical Outcomes in Patients with Traumatic Brain Injury (TBI)
Traumatic Brain Injuries (TBI) pose a substantial global health threat, representing a significant contributor to mortality rates worldwide. TBI is brain damage caused by external force, with varying severity from mild to severe, which can be classified using the Glasgow Coma Scale (GCS). This study aims to investigate the impact of GCS score transitions of penetrating and severe TBI patients from time of admittance to after 24 hours. Data from the Medical Information Mart in Intensive Care (MIMIC)-IV V2.2, at Beth Israel Deaconess Medical Center, was used to run analysis on admission characteristics of TBI patients. Two separate logistic regression models were fitted: one for mortality and one for dispositional outcome. Each model compared data of various patient variables such as Glasgow Coma Scale (GCS), ICU length of stay (LOS), age, gender, and race on the mortality and dispositional outcome of traumatic brain injury (TBI) patients. The data analysis supported that the odds of unfavorable conditions of dispositional outcome and mortality decreased by a factor of 0.136866 and 0.397105 respectively for every one unit increase of GCS. These findings provide crucial insights for enhancing clinical strategies and optimizing care for TBI patients within hospital settings.