Exploring the Potential of Cucurbiturils as Host Compounds in Host-Guest Complexes
Session Number
Project ID: BIO 40
Advisor(s)
Dr. Laura Kopff; Illinois Mathematics and Science Academy
Discipline
Biology
Start Date
22-4-2020 10:25 AM
End Date
22-4-2020 10:40 AM
Abstract
Cucurbiturils (CB[n]) are macrocyclic compounds made from glycoluril monomers. They have the potential to act as host molecules in the formation of host-guest complexes with an array of substrates, including amino acids, hydrocarbons, and halogenated aromatic compounds. Cucurbit[6]uril (CB[6]) and Cucurbit[7]uril (CB[7]) were synthesized and characterized with melting point and solubility data. Their ability to act as host complexes with both coumarin-1 dye and biphenyl was explored using UV-vis spectroscopy. We synthesized CB[6] and CB[7] compounds and made eleven solutions to figure out when combined how the absorbance peaks might change. Three solutions of Coumarin 1 dye and ethanol with concentrations of 50mM, 20mM, and 10mM, four solutions of both CB[7] and CB[7]were made with concentrations of 100mM, 50mM, 20mM, and 10mM. UV-vis spectral analyses were then performed on every individual solution and on combinations of every concentration of the cucurbiturils with every concentration of the coumarin-1 dye.
Exploring the Potential of Cucurbiturils as Host Compounds in Host-Guest Complexes
Cucurbiturils (CB[n]) are macrocyclic compounds made from glycoluril monomers. They have the potential to act as host molecules in the formation of host-guest complexes with an array of substrates, including amino acids, hydrocarbons, and halogenated aromatic compounds. Cucurbit[6]uril (CB[6]) and Cucurbit[7]uril (CB[7]) were synthesized and characterized with melting point and solubility data. Their ability to act as host complexes with both coumarin-1 dye and biphenyl was explored using UV-vis spectroscopy. We synthesized CB[6] and CB[7] compounds and made eleven solutions to figure out when combined how the absorbance peaks might change. Three solutions of Coumarin 1 dye and ethanol with concentrations of 50mM, 20mM, and 10mM, four solutions of both CB[7] and CB[7]were made with concentrations of 100mM, 50mM, 20mM, and 10mM. UV-vis spectral analyses were then performed on every individual solution and on combinations of every concentration of the cucurbiturils with every concentration of the coumarin-1 dye.
Comments
NOTE: This presentation will not take place.