The Effect of Vitamin D on Glioblastoma Multiforme T98G Cells
Session Number
Project ID: BIO 10
Advisor(s)
Dr. Sowmya Anjur, Illinois Mathematics and Science Academy
Discipline
Biology
Start Date
20-4-2022 9:10 AM
End Date
20-4-2022 9:25 AM
Abstract
Vitamin D has been proven to have anti-proliferative effects on several different types of cancer, including Glioblastoma multiforme (GBM). The use of supplemental Vitamin D has demonstrated a reduced mortality rate in GBM patients, and the expression of the Vitamin D Receptor may be associated with a better prognosis for GBM patients. To further establish the tumoricidal efficacy of Vitamin D, GBM was cultured in Vitamin D solutions of varying concentrations. We anticipate proving that Vitamin D induces apoptosis of GBM T98G cells and also confirming the proper concentration(s) of Vitamin D that may be expected to inhibit GBM cell growth.
The Effect of Vitamin D on Glioblastoma Multiforme T98G Cells
Vitamin D has been proven to have anti-proliferative effects on several different types of cancer, including Glioblastoma multiforme (GBM). The use of supplemental Vitamin D has demonstrated a reduced mortality rate in GBM patients, and the expression of the Vitamin D Receptor may be associated with a better prognosis for GBM patients. To further establish the tumoricidal efficacy of Vitamin D, GBM was cultured in Vitamin D solutions of varying concentrations. We anticipate proving that Vitamin D induces apoptosis of GBM T98G cells and also confirming the proper concentration(s) of Vitamin D that may be expected to inhibit GBM cell growth.