Potential Treatments for Mycetoma Using Synthesized Ferinamol Derivatives

Session Number

Project ID: CHEM 05

Advisor(s)

Dr. John Thurmond; Illinois Mathematics and Science Academy

Discipline

Chemistry

Start Date

19-4-2023 10:50 AM

End Date

19-4-2023 11:05 AM

Abstract

Eumycetoma, or fungal infections of mycetoma, plague third world countries. The symptoms of this disease include lesions with fistulae and abscesses filled with pus on the limbs, which sometimes need amputation. The current treatment methods of antifungal antibiotics and antifungal therapy of eumycetoma are currently not very effective. This project’s intention is to synthesize derivatives of Fenarimol, an antifungal agent, to be used as a method to combat eumycetoma. The process involved isolating the fenarimol fungicide using various purification methods, such as column chromatography and thin layer chromatography. This project’s goal is to synthesize and purify a medicinal compound that will help fight fungal infections of mycetoma. This project has successfully synthesized and purified a compound to be tested for usability as a potential treatment for fungal infections of mycetoma.

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Apr 19th, 10:50 AM Apr 19th, 11:05 AM

Potential Treatments for Mycetoma Using Synthesized Ferinamol Derivatives

Eumycetoma, or fungal infections of mycetoma, plague third world countries. The symptoms of this disease include lesions with fistulae and abscesses filled with pus on the limbs, which sometimes need amputation. The current treatment methods of antifungal antibiotics and antifungal therapy of eumycetoma are currently not very effective. This project’s intention is to synthesize derivatives of Fenarimol, an antifungal agent, to be used as a method to combat eumycetoma. The process involved isolating the fenarimol fungicide using various purification methods, such as column chromatography and thin layer chromatography. This project’s goal is to synthesize and purify a medicinal compound that will help fight fungal infections of mycetoma. This project has successfully synthesized and purified a compound to be tested for usability as a potential treatment for fungal infections of mycetoma.