FAV Intake’s Effect on Kidney Filtration
Session Number
Project ID: BIO 13
Advisor(s)
Dr. Santosh Saraf, MD, University of Illinois at Chicago
Discipline
Biology
Start Date
17-4-2024 8:55 AM
End Date
17-4-2024 9:10 AM
Abstract
This study analyzes the connections between reported diet, in terms of fruit and vegetable (FAV) intake, observed serum carotenoid values, and kidney function in people with sickle cell disease. An adequate FAV intake has a beneficial impact on kidney health, and people with sickle cell disease are at much higher risk of medical complications and early mortality if they also develop kidney disease. This study examines the possible effect of FAV intake on kidney health, confirmed by carotenoid levels. Carotenoids, pigments found in fruits and vegetables which are not easily digestible by the human body, are good biomarkers for measuring FAV intake. The self-reported FAV intake is compared with measured carotenoid values to validate the FAV intake and better understand if there is a knowledge gap between perceived and actual FAV intake. We will then compare FAV intake and measured carotenoid values with measures of kidney function (urine albumin concentration and estimated glomerular filtration rate). This study analyzes 3 levels of data from 20 participants with sickle cell disease in the Chicago area. The data collected includes self-reported surveys of FAV intake completed by each participant, blood samples to measure carotenoid concentrations, and measures of their kidney function.
FAV Intake’s Effect on Kidney Filtration
This study analyzes the connections between reported diet, in terms of fruit and vegetable (FAV) intake, observed serum carotenoid values, and kidney function in people with sickle cell disease. An adequate FAV intake has a beneficial impact on kidney health, and people with sickle cell disease are at much higher risk of medical complications and early mortality if they also develop kidney disease. This study examines the possible effect of FAV intake on kidney health, confirmed by carotenoid levels. Carotenoids, pigments found in fruits and vegetables which are not easily digestible by the human body, are good biomarkers for measuring FAV intake. The self-reported FAV intake is compared with measured carotenoid values to validate the FAV intake and better understand if there is a knowledge gap between perceived and actual FAV intake. We will then compare FAV intake and measured carotenoid values with measures of kidney function (urine albumin concentration and estimated glomerular filtration rate). This study analyzes 3 levels of data from 20 participants with sickle cell disease in the Chicago area. The data collected includes self-reported surveys of FAV intake completed by each participant, blood samples to measure carotenoid concentrations, and measures of their kidney function.