Effect of Ayurvedic herbs on U118 Glioblastoma multiforme cell line
Session Number
Project ID: BIO 25
Advisor(s)
Dr. Sowmya Anjur; Illinois Mathematics and Science Academy
Discipline
Biology
Start Date
22-4-2020 8:30 AM
End Date
22-4-2020 8:45 AM
Abstract
Glioblastoma multiforme (GBM) is a stage IV astrocytoma, accounting for over 60% of all brain tumors in adults and a very poor prognosis of just 14-15 months. Despite numerous treatment options currently available, GBM recurs 90% of the time. With barriers in affordability and hesitance toward synthetic medicines, many people have turned to natural treatments for GBM. We tested the cytotoxicity of the U118 GBM cell line when treated with the common Ayurvedic herbs hing (Ferula asafoetida), triphala (a combination of Emblica officinalis, Terminalia bellirica, and Terminalia chebula), and coriander (Coriandrum sativum) using an MTT assay.
Effect of Ayurvedic herbs on U118 Glioblastoma multiforme cell line
Glioblastoma multiforme (GBM) is a stage IV astrocytoma, accounting for over 60% of all brain tumors in adults and a very poor prognosis of just 14-15 months. Despite numerous treatment options currently available, GBM recurs 90% of the time. With barriers in affordability and hesitance toward synthetic medicines, many people have turned to natural treatments for GBM. We tested the cytotoxicity of the U118 GBM cell line when treated with the common Ayurvedic herbs hing (Ferula asafoetida), triphala (a combination of Emblica officinalis, Terminalia bellirica, and Terminalia chebula), and coriander (Coriandrum sativum) using an MTT assay.